@article { author = {Nosrati, Hassan and Sarraf-Mamoory, Rasoul and Le, Dang Quang Svend and Canillas Perez, Maria and Bunger, Cody Eric}, title = {Physical evaluation of 3D-printed gelatin-hydroxyapatite-reduced graphene oxide nanocomposite as a bone tissue engineering scaffold}, journal = {Journal of Tissues and Materials}, volume = {3}, number = {1}, pages = {1-11}, year = {2020}, publisher = {Tissues and Biomaterial Research Group (TBRG)-USERN}, issn = {2645-3487}, eissn = {2676-6981}, doi = {10.22034/jtm.2020.218433.1024}, abstract = {Introduction: HA and graphene have recently been added to gelatin as reinforcing phases (individually or together). These materials increase the mechanical and biological properties of gelatin and extend gelatin applications as tissue engineering scaffolds. Objective: In this study, the physical properties of these scaffolds were evaluated using scanning electron microscopy by detail. Material and Methods: A hydrogel 3D printing method and freeze- drying were used in this study. The analysis performed in the sample includes X-ray diffraction, Scanning Electron Microscope, and bending. Result: The findings of this study showed that the addition of graphene and HA to gelatin changed the rheology, reduced the size of pores, and increased the accuracy of the designed pores. The addition of HA and graphene also increased the bending strength and changed the shape of the resulting cracks. Conclusion: The findings of this study will be useful for the design of bone tissue engineering scaffolds.}, keywords = {Hydroxyapatite,graphene,Scaffold,Gelatin,3D Printing}, url = {https://www.jourtm.com/article_104773.html}, eprint = {https://www.jourtm.com/article_104773_c3a6b6ce99c55127b25ba1a470d88a23.pdf} }