Tissues and Biomaterial Research Group (TBRG)-USERN
Journal of Tissues and Materials
2645-3487
2676-6981
3
4
2020
12
01
The effect of synthesis parameters on structure and properties of silica xerogels
1
5
EN
elmira
banaee mofakham
Department of Nanotechnology and Advanced Materials Research, material and research center, Karaj, Iran.
e.banaee@merc.ac.ir
azadeh
ghaee
Department of life science engineering, faculty of new sciences and technology, university of Tehran, Tehran, Iran
azadeh_ghaee@yahoo.com
arezou
mashak
Iran Polymer and petrochemical institute, Research Instructor, Tehran, Iran
a.mashak@ippi.ac.ir
10.22034/jtm.2020.253674.1032
Introduction<br />Sol gel derived silica matrices have many promising features such as high homogeneity, product purity, chemical and physical stability and porosity. These porous materials with nanosized pores enable loading of numerous biologically active substances into matrices. <br />Objective<br />The aim of this study was to investigate the effect of synthesis parameters on structure of silica xerogels. <br />Methods<br />The effect of two different catalysts (NH4OH and HCl), drying temperature and water content on properties of xerogels were studied. Chemical composition and structure of xerogels were analyzed by Fourier Transfer Infrared Radiation (FTIR) and Scanning Electron Microscopy (SEM), respectively. Specific surface area and pore size of xerogels were examined by BET. <br />Results<br />FTIR results confirmed the forming of Si-O-Si bonds which proved condensation of silanols. According to results, acid-base catalyst, lower temperature for drying and lower water content caused to form crack free xerogels. SEM results showed that acid-base catalyzed xerogels were more porous and pores of acid-base catalyzed xerogels were cylindrical while acid catalyzed xerogels had plate like pores. BET results represented that using higher drying temperature, higher water content and acid-base catalyst increased pore size of xerogel. Also BET results proved that these xerogels had nanosized pores( ̴ 4nm).<br />Conclusion<br />We conclude that different active substances can be entrapped in xerogels by changing synthesis parameters and achieving different pore sizes.
Silica,Xerogel,Sol gel,Catalyst,drying temperature
https://www.jourtm.com/article_122545.html
https://www.jourtm.com/article_122545_9adde802cb64a9d127698b0115a636da.pdf
Tissues and Biomaterial Research Group (TBRG)-USERN
Journal of Tissues and Materials
2645-3487
2676-6981
3
4
2020
10
01
An Overview of Polyaniline in Tissue Engineering
6
22
EN
Bahareh
Kheilnezhad
Department of Biomedical Engineering, Amirkabir University, Tehran, Iran
Alireza
Safaei Firoozabady
Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Amir
Aidun
National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran
amir.aidunn@gmail.com
10.22034/jtm.2020.142186
Electrical response in tissue regeneration has been demonstrate, so growing use of conductive polymers as a main component of scaffolds have developed. Advantages of Polyaniline outweigh other conductive polymers, these including, cost-effective, easy to fabrication, more biocompatible than others, etc. On other hand, cell signaling has been proved as dynamic biochemical that could be promoted cell behaviors such as adhesion, proliferation, and differentiation. In addition, oligoaniline has been emerged to solve some limitation of polyaniline such as biodegradability and biocompatibility problems. Recent researches have been shown that all cells such as cardiac, neural, muscle, bone and fibroblast cells respond to electrical stimulation and to enhance their functions. Bio-mimicking scaffolds is a key role in tissue engineering to achieve a target goal. Hence, the use of polyaniline/oligoaniline has increased. In this review, we investigated properties of polyaniline/oligoaniline and its applications in a variety of tissue engineering.
Polyaniline,Oligoaniline,Tissue engineering applications,Regenerative medicine
https://www.jourtm.com/article_142186.html
https://www.jourtm.com/article_142186_ee9660b04c92cdf58fdda8824b9c6d0b.pdf
Tissues and Biomaterial Research Group (TBRG)-USERN
Journal of Tissues and Materials
2645-3487
2676-6981
3
4
2020
12
01
Three-Dimensional Bioprinting in the neural system
EN
10.22034/jtm.2020.122547
https://www.jourtm.com/article_122547.html
https://www.jourtm.com/article_122547_d41d8cd98f00b204e9800998ecf8427e.pdf