TY - JOUR ID - 159773 TI - Preparation and Evaluation of Chitosan-Carboxymethyl Cellulose Composite Film with Menta longifolia Extract for Wound Healing Activity JO - Journal of Tissues and Materials JA - JTM LA - en SN - 2645-3487 AU - Khalili, Alireza AU - fathi arateh, forough AU - sadat salehi, Tina AU - jafari mousavi, fatemeh sadat AD - Department of Biomedical Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran AD - Department of Biomedical Engineering, Faculty of engineering, Maziar University, Noor, Iran AD - Department of Biomedical Engineering, Tehran center Branch, Islamic Azad University, Tehran, Tehran, Iran AD - Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran Y1 - 2021 PY - 2021 VL - 4 IS - 4 SP - EP - KW - wound dressing KW - Biopolymer KW - Composite KW - Chitosan-Carboxymethyl Cellulose KW - Mentha longifolia Extract DO - 10.22034/jtm.2022.303868.1037 N2 - The aim of this study was to investigate the antibacterial and antifungal properties of Menta longifolia extract on chitosan-carboxymethyl cellulose composite bed for wound making. For this purpose, the effect of the ethanol extract of Oregano plant on the composite film bed of chitosan-carboxymethyl cellulose was investigated. Concentrations of 5%, 10%, 20% ethanolic extracts of oregano leaves with control sample (pure film) were investigated. The results of the experiments and the tests and another showed that Pune extract has antimicrobial properties and is resistant to gram-positive bacteria in the presence of 20% of the extract on the film substrate, more than the sample with concentration Lower extract and pure chitosan-carboxymethyl cellulose film. Also, the presence of Menta longifolia extract with 40% concentration increased the water absorption rate and inflation rate. Surface morphology also showed that increasing the concentration of extract in the film can improve the healing activity of the wound. UR - https://www.jourtm.com/article_159773.html L1 - ER -