2024-03-28T21:01:47Z
https://www.jourtm.com/?_action=export&rf=summon&issue=16804
Journal of Tissues and Materials
JTM
2645-3487
2645-3487
2020
3
3
Comparative analysis of gelatin and hydroxyethyl cellulose scaffolds crosslinked by silane coupling agent
Atefe
Derakhshani
Saeed
Hesaraki
Nader
Nezafati
Mahmoud
Azami
The purpose of this study was to fabricate gelatin (G) and hydroxyethyl cellulose (HEC) scaffolds as promising for skin tissue engineering. Therefore, crosslinking is essential to prepare the mentioned scaffolds. ɣ -Glycidoxypropyltrimethoxysilane (GPTMS) was added to polymeric solutions as a cross-linker agent and then freeze-dried. Scanning electron microscopy (SEM) micrographs indicated that the average pore size of the G-GPTMS and HEC-GPTMS was 54 and 120 µm, respectively. According to the dynamic rheology measurements (DMA), both solutions were flowable in which, the loss modulus was higher than the storage one in HEC-GPTMS and G-GPTMS did not have storage modulus. These loose structures might be depending on the formation of water molecules during sol-gel reaction. Moreover, HEC-GPTMS revealed shear thinning behavior and G-GPTMS showed shear thickening behavior. The G-GPTMS sample showed lower swelling ratio and degradation degrees as compared to HEC-GPTMS scaffold. But due to hydrophilicity and macroporous structures, both scaffolds showed 1700% swelling ratio.
Tissue engineering
swelling ratio
Macroporous
wound healing
2020
11
01
1
10
Journal of Tissues and Materials
JTM
2645-3487
2645-3487
2020
3
3
The Effect of Conductive Biomaterials on the Tissues Engineering
2020
09
01
Journal of Tissues and Materials
JTM
2645-3487
2645-3487
2020
3
3
Recent Advances on the Organ-on-Chip Devices: Focus review
2020
09
01