Tissues and Biomaterial Research Group (TBRG)-USERNJournal of Tissues and Materials2645-34873220200601Synthesis polyurethane closed cell foam via chemical method11006210.22034/jtm.2020.238525.1027ENMohammad Reza GharabeikDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran, IranHassan NosratiDepartment of Materials Engineering, Tarbiat Modares University, Tehran, Iran0000-0003-1509-9819Amir Hossein AhmadiDepartment of Basic Science, Shahed University, Tehran, IranJournal Article20200707Introduction: Possibly the most important class of polymeric foams are polyurethane foams (PUFs), as their thermal conductivity and low density combined with their interesting mechanical properties make them excellent thermal and sound insulators, as well as structural and comfort materials.<br /> Objective: In this study, we demonstrate synthesis polyurethane closed cell foam via a simple chemical method.<br /> Material and Methods: The chemicals used in the study included polyol, foaming agent, silicon oil, and other additives. Characterization methods included X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), elemental map, and Fourier transform infrared spectroscopy (FTIR). <br /> Result: The results of the analysis showed that the obtained foams were successfully synthesized. The cells in these foams were mostly closed, and were micrometric in size. Trace elements were homogeneously distributed in synthesized foams.<br /> Conclusion: The results of this study are expected to be useful for the engineering application of this type of foam.Tissues and Biomaterial Research Group (TBRG)-USERNJournal of Tissues and Materials2645-34873220200601Preparation and characterization of SiC/SiO2 coating by a sol–gel method11006310.22034/jtm.2020.238535.1028ENMohammad Reza GharabeikDepartment of Materials Science and Engineering, Sharif University of Technology, Tehran, IranHassan NosratiDepartment of Materials Engineering, Tarbiat Modares University, Tehran, Iran0000-0003-1509-9819Amir Hossein AhmadiDepartment of Basic Science, Shahed University, Tehran, IranJournal Article20200707Introduction: There are different methods of coating. Depending on the benefits and limitations of each, one method will be optimal.<br /> Objective: The aim of this study is to synthesis SiC-SiO2 coatings with different percentages of SiO2 and SiC.<br /> Material and Methods: By changing the parameters affecting the sol, the percentage of SiO2 and SiC in the coating is adjusted to optimize the mechanical properties such as hardness and wear resistance. The morphology of the coating is examined by scanning electron microscopy (SEM) and transmission electron microscopy (TEM).<br /> Result: Suspensions prepared in an acidic environment are rapidly agglomerated and practically cannot be coated. Suspensions prepared in a neutral environment also settle after a very short time. However, the suspensions and colloids prepared in the alkaline environment have a relatively high stability. Therefore, it can be conclude that pH is the main variable of coating process.<br /> Conclusion: The results of this study are expected to be useful for the engineering application of this type of coating.Tissues and Biomaterial Research Group (TBRG)-USERNJournal of Tissues and Materials2645-348732202006013D bioprinting for bone tissues: materials and design11006810.22034/jtm.2020.110068ENJournal Article20200708Tissues and Biomaterial Research Group (TBRG)-USERNJournal of Tissues and Materials2645-34873220200601Fabricating Polyethylene oxide (PEO) Nanofiber Scaffolds with Different Molecular Weight for Viral Infection Diseases12084810.22034/jtm.2020.120848ENElnaz AhaniDepartment of Nanoengineering, Joint School of Nanoscience and Nanoengineering, North Carolina A&T State UniversityMasumeh DodelMedical Biotechnology Research Center, Paramedicine Faculty, Guilan University of Medical Sciences, Rasht, IranJournal Article20201223Recently, a novel dosage form topical vaginal delivery has been developed utilizing drug-fibers fabricated by electrospinning. Biocompatible and biodegradable nanofiber meshes suitable for drug delivery systems were electrospun based on poly (ethylene oxide) (PEO) with high molecular weight (HMW) and low molecular weight (LMW) to design innovative vaginal delivery systems. It is desirable to encapsulate a drug inside the fibers to enhance the drug antiviral activity in addition to controlling the fiber diameter. The surface morphology and average diameter of the nanofibers were determined by field emission scanning electron microscopy (FE-SEM). Based on SEM results it was revealed that the HMW PEO has more uniform nanofibers with good average diameters than LMW PEO. We formulated acyclovir (ACV) at 20 wt% into electrospun solid dispersions construct from PEO nanofibers and examined distribution in characterizing drug release rates into aqueous media. We assumed that ACV-loaded PEO nanofiber scaffolds were prepared using electrospinning when applied to vaginal environment, should remain undamaged as long as the environment is acidic.